Enucleation vs Pancreatoduodenectomy for Benign and Low-Grade Pancreatic Head Tumors

In this multicenter cohort study, enucleation for benign and low-grade pancreatic head tumors was associated with higher CR-POPF than pancreatoduodenectomy but fewer major complications, less delayed gastric emptying, shorter hospitalization, and superior long-term quality of life. These findings support enucleation as a viable option when technically feasible, particularly for tumors 2.5 cm or smaller; residual tumor size imbalance after matching warrants prospective confirmation.

Corresponding Authors: Rong Liu, MD (liurong@301hospital.com), and Qu Liu, MD (leonliu52@163.com), Faculty of Hepatopancreatobiliary Surgery, First Medical Center of Chinese PLA General Hospital, 28 Fuxing Rd, Beijing 100853, China.

Link to the article in your story

We encourage you to link out to this article in your story using the link below. It includes an access token that will give free access to the article for your readers up to one year after publication. (The link will be live after the article publishes and embargo is lifted.)

Please see the article for additional information, including full author list, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

Need more information? Contact us.