Original Investigation

Enhancement of Patient-Centered Lung Cancer Screening

JAMA Oncology 10.1001/jamaoncol.2025.5672

December 26, 2025 at 11:00 AM EST

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Does adding a patient-facing, electronic health record (EHR)–integrated tool to a clinician-facing clinical decision support system improve the identification and ordering of lung cancer screening?In this randomized clinical trial of 31 303 adults aged 50 to 79 years with uncertain or documented eligibility for lung cancer screening, the EHR-integrated tool significantly increased the identification of screening-eligible patients and the ordering of low-dose computed tomography lung cancer screening.Combining patient-facing and clinician-facing decision support in primary care may enhance lung cancer screening by improving eligibility identification and computed tomography scan ordering.

Corresponding Author: Kensaku Kawamoto, MD, PhD, MHS, Department of Biomedical Informatics, University of Utah, 421 Wakara Way, Ste 108, Salt Lake City, UT 84108 (kensaku.kawamoto@utah.edu).

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