Earlier Disclosure of Blood-Based Biomarkers, Diagnostic Certainty, and Clinical Management

In this randomized clinical trial, earlier disclosure of blood-based biomarkers increased etiologic diagnostic certainty and led to earlier, targeted clinical management without increasing emotional distress. These findings support the integration of blood-based biomarkers into memory clinic diagnostic pathways.

Corresponding Authors: Albert Puig-Pijoan, MD, PhD, Barcelona Brain Health Center, Department of Neurology, Hospital del Mar, Passeig Marítim 25-29, 08003, Barcelona, Spain (apuig@hmar.cat); Marc Suárez-Calvet, MD, PhD, Barcelona Brain Health Center, Department of Neurology, Hospital del Mar, Barcelonaβeta Brain Research Center, Fundació Pasqual Maragall, Wellington 30, 08005, Barcelona, Spain (msuarez@barcelonabeta.org).

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