Original Investigation

Roxadustat Treatment After PCI Among Patients With ST-Segment Elevation Myocardial Infarction

JAMA Network Open 10.1001/jamanetworkopen.2026.37953

October 09, 2026 at 11:00 AM EDT

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In this randomized clinical trial of patients with STEMI, roxadustat administration after PCI did not significantly reduce infarct size at 30 days compared with control. Secondary ventricular remodeling findings were exploratory and require confirmation.

Corresponding Authors: Xiaoxiang Yan, MD, PhD (cardexyanxx@hotmail.com), and Ruiyan Zhang, MD, PhD (zhangruiyan@263.net), Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Rd, Shanghai 200025, PR China.

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