Original Investigation

End-of-Life Antibiotic Use After the Life-Sustaining Treatment Decisions Act in Korea

JAMA Network Open 10.1001/jamanetworkopen.2026.36508

September 29, 2026 at 11:00 AM EDT

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In this retrospective cohort study of patients with advanced cancer, the LSTD Act was not associated with reduced end-of-life antibiotic use, suggesting the need to reshape perceptions of antibiotics as potential life-sustaining therapy.

Corresponding Authors: Jeong-Han Kim, MD, MS, Division of Infectious Diseases, Department of Internal Medicine, Ewha Womans University College of Medicine, Mokdong Hospital, 1071, Anyangcheon-ro, Yangcheon-gu, Seoul, South Korea (wjdgks0525@gmail.com); Shin Hye Yoo, MD, PhD, Center for Palliative Care and Clinical Ethics, Seoul National University Hospital, 103 Daehak-ro, Jongno-gu, Seoul, South Korea (ifi1024@gmail.com).

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