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Adherence to Sedative Weaning Opportunities and Length of Stay for Critically Ill Children

JAMA Network Open 10.1001/jamanetworkopen.2026.29399

August 21, 2026 at 11:00 AM EDT

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In this multicenter cohort, adherence to sedative weaning opportunities was low. Higher weaning adherence was independently associated with shorter ICU and hospital lengths of stay and reduced sedative exposure. Improving adherence to sedative weaning opportunities may represent a modifiable target for reducing length of stay and sedative exposure.

Corresponding Author: John N. Kheir, MD, Department of Cardiology, Boston Children’s Hospital, 300 Longwood Ave, Boston, MA 02115 (john.kheir@childrens.harvard.edu).

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