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Decolonization vs Enhanced Cleaning for Multidrug-Resistant Organism Reduction in Nursing Homes

JAMA Network Open 10.1001/jamanetworkopen.2026.26940

August 05, 2026 at 11:00 AM EDT

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In this quality improvement study, only decolonization was associated with reduced MDRO carriage and bedroom contamination, and only common area contamination appeared to be further reduced by adding once-daily enhanced cleaning.

Corresponding Author: Gabrielle M. Gussin, PhD, Division of Infectious Diseases, University of California Irvine School of Medicine, 100 Theory, Ste 120, Irvine, CA 92617 (gussing@hs.uci.edu).

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