Original Investigation

Antepartum Exposure to Greenness, Air Pollution, and Temperature and Outcomes of Preterm Infants

JAMA Network Open 10.1001/jamanetworkopen.2026.0102

February 26, 2026 at 11:00 AM EST

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Is antepartum exposure to green spaces, air pollutants, and extreme temperatures associated with the neonatal outcomes of preterm infants?In this cohort study of 14 748 extremely preterm infants that used data from linked national environmental and neonatal databases, maternal antepartum exposure to low levels of greenness, high levels of ozone, and low temperatures was associated with significantly lower odds of survival without major morbidity in infants compared with infants born to mothers who were unexposed.The findings suggest that antepartum exposure to environmental stressors is associated with neonatal outcomes of infants born before 29 weeks’ gestation.

Corresponding Author: Prakesh S. Shah, MD, MSc, Department of Pediatrics, Mount Sinai Hospital, Sinai Health, 600 University Ave, Room 19-231, Toronto, ON M5G 1X5, Canada (prakeshkumar.shah@sinaihealth.ca).

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