Original Investigation

A Pharmacist Consultant Service for Deprescribing Opioids and Benzodiazepines in Older Adults

JAMA Network Open 10.1001/jamanetworkopen.2025.60581

February 26, 2026 at 11:00 AM EST

Read the full article

What impact does a pharmacist consultant service have on deprescribing rates of opioids and benzodiazepines in older adults?In this cluster randomized trial of 15 primary care clinics with 961 and 1107 older adults taking long-term opioids and benzodiazepines, respectively, reductions in morphine and diazepam milliequivalents were achieved in both the intervention and control groups. There was no statistically significant reduction in medication use or falls.These results suggest that a consultant pharmacist–led intervention is feasible to implement in primary care clinics.

Corresponding Author: Stefanie P. Ferreri, PharmD, Division of Practice Advancement and Clinical Education, University of North Carolina at Chapel Hill, UNC Eshelman School of Pharmacy, 1309 Kerr Hall, CB 7574, Chapel Hill, NC 27599 (stefanie_ferreri@unc.edu).

Link to the article in your story

We encourage you to link out to this article in your story using the link below. It includes an access token that will give free access to the article for your readers up to one year after publication. (The link will be live after the article publishes and embargo is lifted.)

Please see the article for additional information, including full author list, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

Need more information? Contact us.

Editor's Picks