Pharmacist Intervention for Safer Prescribing in Patients With Type 2 Diabetes at High Risk
JAMA Network Open 10.1001/jamanetworkopen.2025.59946February 18, 2026 at 11:00 AM EST
Does proactive outreach by a clinical pharmacist applying an evidence-based hypoglycemia-prevention algorithm result in safer diabetes regimens among patients with type 2 diabetes at high risk of hypoglycemia?In this randomized clinical trial of 200 adults, patients in the intervention arm (proactive outreach by the pharmacist) were statistically significantly more likely to be prescribed a safer diabetes regimen compared with those in the usual care arm (28% vs 16%).The findings of this study suggest that proactive, protocol-driven outreach by clinical pharmacists as part of collaborative team-based care leads to safer diabetes medication prescribing in patients with type 2 diabetes at high risk of hypoglycemia.
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