Original Investigation

Infant Respiratory Syncytial Virus Immunization Through Maternal Vaccination and Nirsevimab

JAMA Network Open 10.1001/jamanetworkopen.2025.59663

February 16, 2026 at 11:00 AM EST

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What factors were associated with receipt of respiratory syncytial virus (RSV) immunization by maternal RSV vaccine or nirsevimab in infants during the 2023-2024 and 2024-2025 RSV seasons?In this cohort study of 13 195 infants who were seen for medical care before 8 months of age, 58% of 6245 infants and 75% of 6950 infants received maternal RSV vaccine or nirsevimab in the 2023-2024 and 2024-2025 RSV seasons, respectively. Infants with public insurance had lower odds of receiving either type of RSV immunization.These findings suggest that despite improved RSV immunization, socioeconomic differences affected receipt of RSV immunization in infants.

Corresponding Author: Karen P. Acker, MD, 505 E 70th St, NY, NY 10021 (kpa9002@med.cornell.edu).

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