Cost-Effectiveness of Home-Based Self-Sampling vs Clinician Sampling for Anal Precancer Screening

What is the cost-effectiveness of home-based vs clinic-based anal cancer screening in increasing screening uptake among sexual and gender minority (SGM) groups in the US?In this economic evaluation of a randomized clinical trial involving 240 SGM men and transgender women, the incremental cost-effectiveness ratio for increased screening uptake was $132.36 from the health care payer perspective and $25.19 from the societal perspective per additional completed screening.These findings suggest that home-based anal cancer screening is a cost-effective strategy for increasing screening participation among SGM individuals, particularly from a societal perspective, as it reduces travel and time-related costs.

Corresponding Author: Haluk Damgacioglu, PhD, Department of Public Health Sciences, Medical University of South Carolina, 86 Jonathan Lucas St, Charleston, SC 29424 (damgacio@musc.edu).

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