Measurement-Based Care to Enhance Antidepressant Treatment Outcomes in Major Depressive Disorder

Does measurement-based care (MBC) reduce time to response and time to remission compared with standard care for major depressive disorder (MDD) in a low- and middle-income country such as Pakistan?In a randomized clinical trial of 154 adults with nonpsychotic MDD, the time to response and time to remission were half as long among those who received MBC compared with those who received standard care.Findings of this trial indicate that MBC may improve treatment outcomes for MDD in resource-limited settings such as Pakistan.

Corresponding Authors: Muhammad Ishrat Husain, MD, Centre for Addiction and Mental Health, 1025 Queen St W, Toronto, ON M6J 1H1, Canada (Ishrat.husain@camh.ca); Benoit H. Mulsant, MD, Department of Psychiatry, University of Toronto, 250 College St, #835, Toronto, ON, M5T 1R8, Canada (benoit.mulsant@utoronto.ca).

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