Original Investigation

Anaplastic Large Cell Lymphoma of the Breast by Race and Ethnicity

JAMA Network Open 10.1001/jamanetworkopen.2025.28013

September 02, 2025 at 11:00 AM EDT

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What are the incidence rates of anaplastic large cell lymphoma (ALCL) of the breast in the US based on race and ethnicity?In this cohort study including 90 women with breast ALCL, incidence rates of breast ALCL were highest and increased most rapidly among Hispanic and non-Hispanic White patient populations, while only a few cases were reported in American Indian or Alaska Native, Asian or Pacific Islander, and Black populations from 2000 to 2020.There are notable racial and ethnic differences in the incidence rates of breast ALCL in the US, the reasons for which are not completely known and deserve further investigation.

Corresponding Author: Connor J. Kinslow, MD, Department of Radiation Oncology, Columbia University Irving Medical Center, 622 W 168th St, New York, NY 10032 (cjk2151@cumc.columbia.edu).

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