Original Investigation

Device-Free Auricular Acupressure for Rosacea

JAMA Dermatology 10.1001/jamadermatol.2026.3999

October 14, 2026 at 11:00 AM EDT

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This randomized clinical trial found that device-free, on-demand intervention yielded substantial additional clinical benefits when combined with standard first-line therapy and established early sham-controlled, serum-based evidence for its neuroimmunomodulatory mechanism, potentially offering a strategy for self-management of rosacea.

Corresponding Authors: Jiawen Wu, PhD, Department of Dermatology, The Second Affiliated Hospital of Xi’an Jiaotong University, No. 157 Xiwu Rd, Xi’an City, Shaanxi Province, China (jiawen702@126.com); Peng An, MM, Department of Traditional Chinese Medicine, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China (anpeng@xjtu.edu.cn).

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