Observation

Topical β-Blocker Wet Wrap Therapy for Amivantamab-Induced Scalp and Facial Necrosis

JAMA Dermatology 10.1001/jamadermatol.2025.3122

September 10, 2025 at 11:00 AM EDT

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This case report describes 2 patients with amivantamab-induced scalp and facial necrosis whose symptoms improved with topical β-blocker wet wrap therapy treatment.

Corresponding Author: Chun-Wei Lu, MD, Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital, Linkou, No. 5, Fuxing Street, Taoyuan, 333 Taiwan (c.wei.lu@gmail.com).

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