Local Recurrence and Survival in Patients With Melanoma In Situ

What is the frequency of local recurrence in non-lentigo maligna /non-acral lentiginous melanoma in situ (non-LM/non-ALM MIS)?In this cohort study of 401 patients with 403 non-LM/non-ALM MIS and follow-up extending up to 26 years (median, 5.2 years), no local recurrences, metastasis, or melanoma-specific death were observed among patients with histologically clear margins treated with initial excisional biopsy alone or via wide excision.For non-LM/non-ALM MIS, clear histopathological margins either at excisional biopsy or after wide excision may be sufficient, although further studies comparing this approach with current standard management are needed.

Corresponding Author: Clio Dessinioti, MD, 1st Department of Dermatology-Venereology, National and Kapodistrian University of Athens, Andreas Sygros Hospital, 5, Dragoumi Str, 16 121, Kaisariani, Athens, Greece (cliodes@hotmail.com).

Link to the article in your story

We encourage you to link out to this article in your story using the link below. It includes an access token that will give free access to the article for your readers up to one year after publication. (The link will be live after the article publishes and embargo is lifted.)

Please see the article for additional information, including full author list, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

Need more information? Contact us.