Physiology-Guided Complete Revascularization in Older Patients With Myocardial Infarction

Is the benefit associated with physiology-guided complete revascularization sustained over time in older patients with myocardial infarction (MI)?This randomized clinical trial involved 1445 patients with MI and multivessel disease who received either culprit-only treatment or physiology-guided complete revascularization of nonculprit lesions. At 3 years, the primary composite outcome of death, MI, stroke, and ischemia-driven revascularization occurred in 165 patients (22.9%) in the physiology-guided complete revascularization group and 216 patients (29.8%) in the culprit-only group.The benefit associated with physiology-guided complete revascularization in older patients with MI is sustained over time and maintained at 3 years.

Corresponding Author: Simone Biscaglia, MD, Cardiology Unit, Azienda Ospedaliera Universitaria S. Anna, Via Aldo Moro 8, Cona (FE) 44124, Italy (bscsmn@unife.it).

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