Original Investigation

Permissive Blood Pressure Targets in Pediatric Critical Care

JAMA 10.1001/jama.2026.19747

September 28, 2026 at 11:30 PM EDT

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Adopting a permissive MAP target resulted in no significant difference in mortality and duration of invasive ventilation at 30 days compared with usual care.

Corresponding Author: David P. Inwald, MB, BChir, PhD, Paediatric Intensive Care Unit, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge CB2 0QQ, United Kingdom (di260@cam.ac.uk).

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