Childhood Cancer Risk After Assisted Reproductive Technology

ART, particularly frozen embryo transfer and intracytoplasmic sperm injection, was associated with increased childhood cancer risk, but absolute risks were low. The consistent results in secondary analyses of children with maternal infertility history or conceived via IVF suggest that procedure-related, rather than infertility-related, factors warrant further investigation.

Corresponding Author: Marie Hargreave, PhD, Virus, Lifestyle and Genes, Danish Cancer Institute, Strandboulevarden 49, DK-2100 Copenhagen, Denmark (mariehar@cancer.dk).

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