Original Investigation

Hospital Adoption and Pricing for Oncology Biosimilars

JAMA 10.1001/jama.2026.1777

March 11, 2026 at 11:00 AM EDT

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How have acquisition prices, reimbursement prices, and adoption of oncology biosimilars changed in recent years?In 66 139 patients with cancer between 2020 and 2024, hospital acquisition prices for 3 oncology biosimilars declined more rapidly than reimbursement prices, leading to an increase in hospital margin revenues. The percentage share of biosimilars increased to 93% for bevacizumab, 87% for trastuzumab, and 84% for rituximab by 2024.Declining prices for oncology biosimilars have enabled hospitals to increase markup margins and have been associated with rapid increases in adoption.

Corresponding Author: James C. Robinson, PhD, University of California, Berkeley, Berkeley, CA 94720-7360 (james.robinson@berkeley.edu).

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