Research Letter

Leading Cancer Deaths in People Younger Than 50 Years

JAMA 10.1001/jama.2025.25467

January 22, 2026 at 11:00 AM EST

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This study examines changes in cancer mortality in the US for the 5 leading cancer-related deaths among people younger than 50 years over the past 3 decades.

Corresponding Author: Rebecca L. Siegel, MPH, American Cancer Society, 270 Peachtree St NW, Ste 1300, Atlanta, GA 30303 (rebecca.siegel@cancer.org).

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