Viewpoint

Uncertainty and Ethical Permissibility in Youth Gender Care

JAMA Pediatrics 10.1001/jamapediatrics.2026.2928

August 03, 2026 at 11:00 AM EDT

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This Viewpoint discusses how misuse of evidence-based medicine displaces the pediatric ethical principles of proportionality and shared decision-making and risks precluding both access to care and generation of evidence needed to reduce uncertainty.

Corresponding Author: Meredithe McNamara, MD, MSc, Yale School of Medicine, 15 York St, New Haven, CT 06510 (meredithe.mcnamara@yale.edu).

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