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Suzetrigine for Postoperative Pain in Head and Neck Free Flap or Transoral Robotic Surgery

JAMA Otolaryngology–Head & Neck Surgery 10.1001/jamaoto.2026.2673

September 17, 2026 at 11:00 AM EDT

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In this cohort study, adjunctive suzetrigine use was associated with lower postoperative opioid requirements after head and neck free flap reconstruction and transoral robotic surgery. Given the retrospective, nonrandomized design, these findings should be interpreted as associations warranting prospective confirmation.

Corresponding Author: Hilary C. McCrary, MD, MPH, Department of Otolaryngology–Head and Neck Surgery, University of Utah, 50 N Medical Dr, SOM 3C120, Salt Lake City, UT 84132 (hilary.mccrary@hci.utah.edu).

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