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Electronic Patient-Reported Outcome Monitoring With Alert-Based Interventions in Metastatic Breast Cancer

JAMA Oncology 10.1001/jamaoncol.2026.2661

August 06, 2026 at 11:00 AM EDT

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This randomized clinical trial found that digital PRO monitoring was associated with clinically meaningful reductions in fatigue and improved physical functioning. These findings support further evaluation of alert-based PRO monitoring in routine oncology care.

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Corresponding Author: Maria Margarete Karsten, Dr habil, Department of Gynecology with Breast Center, Charité–Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany (maria-margarete.karsten@charite.de).

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