TDP-43–Associated Neurodegenerative Disease Conceptualization and Integrated Staging

In proposing a pathobiological definition of disease, the goal is to provide a road map for developing biomarkers that accurately reflect the underlying pathobiology of disease and for advancing therapeutic candidates that effectively target fundamental disease mechanisms.

Corresponding Author: Michael Benatar, MD, PhD, Department of Neurology and the ALS Center, University of Miami Miller School of Medicine, 1120 NW 14 St, CRB 1318, Miami, FL, 33136 (mbenatar@miami.edu).

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