Urolithin A and Endothelial and Cerebrovascular Function in Middle-Aged Adults With Obesity

In this randomized clinical trial of 50 participants, 4 weeks of UA supplementation did not significantly improve peripheral endothelial function in middle-aged adults with obesity. However, supplementation was well tolerated and feasible, and its effect on task-evoked cerebrovascular hemodynamic responses warrants further investigation.

Corresponding Author: Andriy Yabluchanskiy, MD, PhD, Department of Neurosurgery, College of Medicine, University of Oklahoma Health Campus, 1122 NE 13th St, Ste C1-210, Oklahoma City, OK 73117 (andriy-yabluchanskiy@ou.edu).

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