Maternal Influenza Infection During Pregnancy and Neuropsychiatric Disorders in Offspring

In this binational cohort study of mother-child pairs in South Korea and Japan, the modest population-level association between maternal influenza infection during pregnancy and the risk of any neuropsychiatric disorder in offspring was attenuated and not statistically significant in sibling-comparison analyses in either cohort. These findings suggest that familial factors may account for the association observed in the population-level analysis.

Corresponding Author: Dong Keon Yon, MD, PhD, Department of Pediatrics, Kyung Hee University College of Medicine, 23 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, South Korea (yonkkang@gmail.com).

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