Early Mitral Valve Surgery and Survival in Asymptomatic Severe Primary Mitral Regurgitation

In this multicenter cohort study with a target trial framework, early surgery was associated with improved long-term survival among patients with asymptomatic severe primary MR. These findings support consideration of earlier surgical intervention in contemporary clinical practice.

Corresponding Author: Seung-Pyo Lee, MD, PhD, Professor, Department of Internal Medicine, Seoul National University College of Medicine sproll1@snu.ac.kr& Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea (won1@snu.ac.kr).

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