Research Letter

Pembrolizumab vs Nivolumab as Initial Treatment for Advanced, Unresectable, or Metastatic Melanoma

JAMA Network Open 10.1001/jamanetworkopen.2026.36432

September 29, 2026 at 11:00 AM EDT

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This comparative effectiveness research study examines outcomes associated with pembrolizumab and nivolumab among US veterans with advanced, unresectable, or metastatic melanoma.

Corresponding Author: Alex K. Bryant, MD, MAS, Department of Radiation Oncology, Veterans Affairs Ann Arbor Healthcare System, 2215 Fuller Rd, Ann Arbor, MI 48105 (Alex.bryant@va.gov).

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