AI Chatbot Use for Human Papillomavirus Vaccine Literacy in Japan

In this RCT of female caregivers in Japan, an AI-driven HPV vaccine chatbot produced higher adjusted HPV vaccine literacy than a government leaflet immediately after intervention and at 2-week follow-up, without a measurable short-term effect on vaccination decision. Conversational AI may complement official materials and health care professional recommendations.

Corresponding Author: Leesa Lin, PhD, London School of Hygiene and Tropical Medicine Faculty of Epidemiology and Public Health, Keppel Street London WC1E 7HT United Kingdom (leesa.lin@lshtm.ac.uk).

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