Emerging Patterns in Dietary Supplement Use Among US Adults, 1999-2023

What are the long-term trends in dietary supplement use among US adults?In this repeated cross-sectional analysis of 11 National Health and Nutrition Examination Survey cycles from 1999 through 2023 including 63 442 adults, supplement use increased from 51% to 60%, largely after 2009 to 2010, with the greatest increases among older adults. Growth reflected increased use of vitamins, minerals, and nonvitamin nonmineral supplements, including products marketed for immune, anti-inflammatory, gut, and skin or joint health, while multivitamin-multimineral use declined.Increase and diversification of supplement use among US adults underscores the need for continuous population-level monitoring to inform clinical and public health guidance.

Corresponding Author: Chun Sing Lam, PhD, Integrative Medicine and Wellness Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, 321 E 61st St, New York, NY 10065 (lamc3@mskcc.org).

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