Invasive Group A Streptococcal Disease in Persons Experiencing Postpandemic Homelessness in Canada

During the post–COVID-19 pandemic resurgence, how did invasive group A streptococcal (iGAS) infection compare between persons experiencing homeless (PEH) and housed persons?This cross-sectional study demonstrated that iGAS increased among both PEH and housed persons; PEH were less likely to be immunocompromised, but more likely to be persons who inject drugs, to have nonintact skin, and to present with soft tissue infection. iGAS was 70.7-fold more common among PEH than housed persons and types causing disease were different between the groups.The post–COVID-19 pandemic iGAS resurgence included PEH despite very different iGAS epidemiology between PEH and housed persons.

Corresponding Author: Allison McGeer, MD, Mount Sinai Hospital, 600 University Ave, Room 171, Toronto, ON M5G 1X5, Canada (allison.mcgeer@sinaihealth.ca).

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