Original Investigation

Global Burden of Violence Against Transgender and Gender-Diverse Adults

JAMA Network Open 10.1001/jamanetworkopen.2025.52953

January 21, 2026 at 11:00 AM EST

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What is the global burden of interpersonal violence against transgender and gender-diverse adults?In this systematic review and meta-analysis of 94 studies published in 137 articles (65 608 participants), the pooled prevalence of physical or sexual global violence across studies was 64% for lifetime and 60% for recent violence. The pooled prevalence of lifetime physical violence was 36%, and that of sexual violence was 33%.The findings suggest that experiences of interpersonal violence are highly prevalent among transgender and gender-diverse adults globally; there is an urgent need to address such violence through implementation of evidence-based violence prevention and response strategies across settings.

Corresponding Author: Erin E. Cooney, PhD, Department of International Health, Johns Hopkins University Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD 21205 (ecooney2@jhmi.edu).

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