Original Investigation

Streamlined Self-Collection Screening for Sexually Transmitted Infections and Human Papillomavirus

JAMA Network Open 10.1001/jamanetworkopen.2025.51345

January 08, 2026 at 11:00 AM EST

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What is the prevalence of human papillomavirus (HPV) and other sexually transmitted infections (STIs) with simultaneous testing of mailed self-collection kits in a population of low-income women?In this secondary analysis of a randomized clinical trial including 327 intervention participants, nearly 1 in 6 participants tested positive for other STIs, the same rate as those positive for HPV.These findings suggest that streamlining testing for both HPV and other STIs may address multiple preventive care needs among underscreened women.

Corresponding Author: Anisha P. Ganguly, MD, MPH, The University of North Carolina at Chapel Hill School of Medicine, 200 N Greensboro St, Ste C-1, Carrboro, NC 27510 (Anisha_ganguly@med.unc.edu).

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