Postoperative Antimicrobial Prophylaxis Use and Outcomes in Pectus Excavatum Repair

In children undergoing minimally invasive pectus excavatum repair, is the use of postoperative antimicrobial prophylaxis associated with improved outcomes?In this propensity score–matched multicenter cohort study of 3552 children from 141 hospitals, use of postoperative prophylaxis was not associated with a reduction in rates of surgical site infection, reoperation, or hospital readmission.In this study, postoperative continuation of antimicrobial prophylaxis was not associated with improved outcomes and should be reconsidered in children undergoing minimally invasive pectus excavatum repair.

Corresponding Author: Shawn J. Rangel, MD, MSCE, Department of Surgery, Boston Children’s Hospital, Harvard Medical School, 300 Longwood Ave, Fegan-3, Boston, MA 02115 (shawn.rangel@childrens.harvard.edu).

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