Original Investigation

Mobile App–Based Intervention and Cardiovascular Risk Factors in Patients With Uncontrolled Type 2 Diabetes

JAMA Network Open 10.1001/jamanetworkopen.2025.29762

September 02, 2025 at 11:00 AM EDT

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Can a mobile message–based intervention improve cardiovascular risk factors among patients with uncontrolled type 2 diabetes?In this 12-month randomized clinical trial of 819 adults with uncontrolled type 2 diabetes comorbid with cardiovascular disease risk factors, when compared with usual care, adults receiving the message-based intervention had significant improvements in hemoglobin A levels and systolic blood pressure.These findings suggest that mobile message–based strategies for improving glycemic control and cardiovascular disease risk factors should be considered for adults with type 2 diabetes.

Corresponding Authors: Hui-Jie Zhang, MD, PhD, Department of Endocrinology and Metabolism, Nanfang Hospital, Southern Medical University, 1838 N Guangzhou Ave, Guangdong 510515, China (huijiezhang2005@126.com); Zhi-Min Ma, MD, PhD, Department of Endocrinology, Suzhou Research Center of Medical School, Suzhou Hospital, Affiliated Hospital of Medical School, Nanjing University, No. 1 Lijiang Rd, Suzhou New District, Jiangsu 215153, China (mazhimin01@sina.com).

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