Original Investigation

Transcutaneous Auricular Vagus Nerve Stimulation for Postpartum Contraction Pain During Elective Cesarean Delivery

JAMA Network Open 10.1001/jamanetworkopen.2025.29127

August 29, 2025 at 11:00 AM EDT

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What is the effect of transcutaneous auricular vagus nerve stimulation (taVNS) on postpartum uterine contraction pain among women undergoing elective cesarean delivery?This randomized clinical trial involving 156 women undergoing cesarean delivery found that 3 sessions of taVNS reduced the uterine contraction pain scores and incision pain scores during the 3 days postoperatively compared with sham stimulation.These findings suggest that taVNS would be a safe and effective treatment for alleviating postpartum uterine contraction pain among women after cesarean delivery.

Corresponding Authors: He Liu, MD, PhD, Department of Anesthesiology lh121061@163.com& Clinical Research Center for Anesthesia and Perioperative Medicine, Huzhou Central Hospital, Huzhou, China (caojl0310@aliyun.com).

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