Original Investigation

Body Mass Index and Postsurgical Outcomes in Older Adults

JAMA Network Open 10.1001/jamanetworkopen.2025.28875

August 26, 2025 at 11:00 AM EDT

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In older adults (≥65 years) presenting for surgery, is higher body mass index associated with lower 30-day all-cause mortality?In this cohort study of 414 participants, patients categorized as being overweight had the lowest 30-day all-cause mortality rate compared with patients categorized as having a normal body mass index.These findings suggest traditional body mass index risk categories may need to be recalibrated for the population aged 65 years and older undergoing surgery.

Corresponding Author: Cecilia Canales, MD, MPH, MS, Department of Anesthesiology and Perioperative Medicine, UCLA David Geffen School of Medicine, 757 Westwood Plaza, Room 3304, Los Angeles, CA 90095 (ceciliacanales@mednet.ucla.edu).

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