Traumatic Brain Injury and Risk of Malignant Brain Tumors in Civilian Populations

Is a history of traumatic brain injury (TBI) associated with increased risk of developing a malignant brain tumor among civilian populations?In this cohort study including 151 358 US adult civilians, the risk of developing a malignant brain tumor was significantly higher among adults with TBI compared with those without TBI.These findings suggest that additional evaluation and monitoring may be warranted for adult civilians with TBI to detect the potential development of malignant brain tumors.

Corresponding Authors: Saef Izzy, MD, Department of Neurology, Massachusetts General Hospital, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA (sizzy@bwh.harvard.edu); and Ross Zafonte, DO, Physical Medicine and Rehabilitation, University of Missouri School of Medicine, MU Health, Columbia, MO 65212 (rzbg3@health.missouri.edu).

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