Original Investigation

Global, Regional, and National Burden of Heart Failure, 1990-2023

JAMA Cardiology 10.1001/jamacardio.2026.4068

September 30, 2026 at 11:00 AM EDT

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Heart failure is a significant global public health burden, and the impact is likely to increase as populations age. However, most HF etiologies can be prevented by interventions that reduce exposure to modifiable risk factors, such as elevated blood pressure, excessive alcohol consumption, and tobacco use. Etiology- and location-specific estimates can provide necessary information for public health officials to determine how best to prioritize interventions to reduce HF disease burden.

Corresponding Author: Catherine O. Johnson, PhD, MPH, Institute for Health Metrics and Evaluation, University of Washington, 3980 15th Ave NE, UW Box 351615, Seattle, WA 98195 (johnsoco@uw.edu).

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