Review

Type 1 Diabetes

JAMA 10.1001/jama.2026.0048

February 16, 2026 at 11:00 AM EST

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Type 1 diabetes accounts for 5% to 10% of all cases of diabetes and is characterized by the presence of islet autoantibodies in 90% to 95% of patients. Lifelong use of insulin therapy is currently required for treatment of type 1 diabetes.

Corresponding Author: Desmond A. Schatz, MD, University of Florida, 1275 Center Dr, Gainesville, FL 32608 (schatz@ufl.edu).

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