Antibiotic Therapy for Uncomplicated Acute Appendicitis

What is the long-term appendicitis recurrence and appendectomy rate in adult patients with uncomplicated acute appendicitis treated with antibiotics?In this 10-year observational follow-up of patients initially treated with antibiotics for uncomplicated acute appendicitis, the true appendicitis recurrence rate (appendicitis at histopathology) was 37.8% and the cumulative appendectomy rate was 44.3%.Long-term follow-up of patients with uncomplicated acute appendicitis supports the use of antibiotics as an option for uncomplicated acute appendicitis in adult patients.

Corresponding Author: Paulina Salminen, MD, PhD, Department of Surgery, University of Turku, PO Box 52, 20520 Turku, Finland (paulina.salminen@varha.fi).

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