Partial Heart Transplant for Congenital Heart Disease

Does partial heart transplant provide a safe and effective valve replacement option that also has capacity for growth in patients with congenital heart disease?In this case series of 19 patients who underwent partial heart transplant, all valves demonstrated functional durability and growth over time with maintenance immunosuppression. No patient experienced valve-related reintervention, and leaflet measurements confirmed true tissue growth.Partial heart transplant appears to be a safe and feasible procedure that enables valve growth, representing a promising solution to overcome the limitations of current nongrowing valve replacement options.

Corresponding Author: Joseph W. Turek, MD, PhD, MBA, Division of Thoracic and Cardiovascular Surgery, Department of Surgery, Duke University Medical Center, 2301 Erwin Rd, DUMC 3474, Durham, NC 27710 (joseph.turek@duke.edu).

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