Long-Term Opioid Therapy for Pain

This Viewpoint discusses recent US Food and Drug Administration data on opioid-related risks and harms; highlights ways in which understanding of these risks and harms remains incomplete; and calls for required postmarketing opioid studies and improved regulatory communications to ensure safer, more effective pain care.

Corresponding Author: Mark C. Bicket, MD, PhD, 1500 E Medical Center Dr, Ann Arbor, MI 48109 (mbicket@med.umich.edu).

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